Let us show you a range of possibilities of how to measure the textural properties of of pharmaceutical and medical products with a texture analyser.
Measure a multitude of textures from raw ingredients to finished product.
The stability of a pharmaceutical product is paramount to the consumer's acceptance of it, as well as to its subsequent efficacy and safety. Development of new excipients and drug delivery systems can be challenging as effectiveness, and perhaps cost, benefits can be mitigated when quality control problems arise during manufacturing.
It is vital, therefore, that manufacturers scientifically assess any potential changes in the structure or character of their products throughout formulation, processing and distribution. That is where texture analysis plays a role in providing repeatable and actional test data on the effects on physical quality of active ingredients, inactive ingredients and finished products such as packaging for sterile products, tablets and tablet coatings, gels and transdermal delivery systems.
Tissue Engineering and Regenerative Medicine research, meanwhile, relies upon the mechanical function of engineered tissues as a primary endpoint for the successful regeneration of many biological tissues. This needs to be characterised and compared to initial benchmark function to determine quality control standards for the next generation of health care.
As the pharmaceutical industry innovates, so our materials analysis evolves, developing and adapting to provide new test solutions and methodologies for emerging requirements. When a test solution doesn’t exist we go ahead and develop it – the Tablet Disintegration Rig, Capsule/Loop Tensile Rig and Granule Compaction Rig are classic examples of our Community Registered Designs.
A wide range of PHARMACEUTICAL & MEDICAL PRODUCT test methods is built into Exponent Texture Analyser software and will automatically load at the click of a button. We help make your testing quicker to access and the analysis of your product properties already prepared for you.
Typical measurements include: • Powder compaction force • Granule compressibility / fracture strength • Hardness • Mechanical / tensile strength • Bilayer separation force • Disintegration rates • Swelling behaviour • Burst strength • Peeling characteristics • Extrudability • Gel strength • Mucoadhesion
No one knows more about the texture analysis of pharmaceutical and medical products – but don’t just take our word for it, read an example of what our customers have to say.
Any of the texture analyser range can be used for the product tests listed.
A selection of special attachments and typical measurements which are commonly used in this application area are shown, although this does not necessarily include the complete range available for the testing of pharmaceutical and medical products. Test procedures include: compression, puncture / penetration, tension, fracture / bending, extrusion, cutting / shearing.